How about it...covers that take a song and play it in a very different style.
This one is great: Every Rose Has Its Thorn (originally by Poison), covered by the "Pickin' On" bluegrass cover series (and brought to me by the Coverville podcast, great podcast, though a couple crappy episodes lately):
http://coverville.com/archives/2009/...post-valentine
Or, straight to the MP3 of that episode:
http://feedproxy.google.com/~r/cover...lle-090216.mp3
He Stopped Loving Her Today, as covered by Trent Summar & The New Row Mob...the verses are done in the original George Jones style, but the refrain is done in some heavy punk style or something. This live performance sucks, but the album version is very cool.
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Just found this on Coverville, it's a great one-man multi-track cover of Africa (originally by Toto).
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Edit: Ok, so that last one wasn't cross-genre. D'oh!